Changes between Version 46 and Version 47 of UTGBMedaka/Track


Ignore:
Timestamp:
09/05/07 13:50:18 (18 years ago)
Author:
ssksn
Comment:

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  • UTGBMedaka/Track

    v46 v47  
    128128
    129129This track displays all the polymorphisms regions between medaka Hd-rR and HNI strain.
     130
     131In addition to the genome of the Hd-rR medaka inbred strain,
     132the genome of another inbred strain HNI was also sequenced to produce the draft 648-Mb HNI genome.
     133Inbred strains Hd-rR and HNI originated in the southern and northern Japanese populations, respectively.
     134They can mate and produce healthy offspring,
     135although they are estimated to have diverged about 4 million years ago,
     136and their genome sequences have diverged by approximately 3.42%.
     137The alignment of the two medaka genomes identified
     138about 16.4 million single nucleotide polymorphisms (SNPs), from which 2,401 SNPs were selected
     139and mapped genetically onto medaka chromosomes using a backcross panel between these two inbred strains.
     140
     141The alignment of the Hd-rR and HNI genomes revealed 16,519,460 SNPs and 2,859,905 insertions/deletions (indels),
     142and the locations of individual SNPs and indels are given in the web database.
     143Pink indicates matched bases, while mismatches are highlighted by green, yellow, blue, and red that represent A, C, G, and T, respectively, in the HNI genome.
     144Cyan indicates the two possibilities, deletions from the HNI genome or insertions into the Hd-rR genome,
     145though the settlement requires comparison with the genome of an outgroup of Hd-rR and HNI.
     146Gray means the failure of the alignment because of low quality bases in either of the two genomes or lack of HNI reads in the region.
     147
    130148The details of this track is described here: http://medaka3.utgenome.org/~ssksn/HNI_SNPs/common/HNI_SNPs_description.html
    131149